发明名称 Combination of antibiotic and nucleic acid binding compound for bacterial antibiotic resistance
摘要 The present invention is drawn to methods of killing bacteria, including antibiotic resistant bacteria, by contacting said bacteria with a membrane permeabilizing compound or combination of compounds and a membrane impermeant toxic agent or combination of agents, resulting in the death of the bacteria without substantial injury to the infected host or patient. The present invention is also drawn to compositions and kits for effecting the method of the present invention. The present invention is further drawn to methods of rendering toxic agents such as toxic organic molecules, membrane impermeant for use in the methods and compositions of the present invention.
申请公布号 AU3906800(A) 申请公布日期 2000.10.09
申请号 AU20000039068 申请日期 2000.03.21
申请人 HOWARD M. SHAPIRO 发明人 HOWARD M. SHAPIRO
分类号 G01N33/50;A61K31/00;A61K31/275;A61K31/397;A61K31/407;A61K31/409;A61K31/4164;A61K31/42;A61K31/425;A61K31/426;A61K31/427;A61K31/43;A61K31/473;A61K31/54;A61K31/545;A61K31/7042;A61K31/7048;A61K45/00;A61K45/06;A61P31/00;A61P31/04;A61P31/10;A61P33/00;C12Q1/02;G01N33/15 主分类号 G01N33/50
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