发明名称 |
Imidazole compounds |
摘要 |
Compounds represented by general formula (I) or pharmacologically acceptable salts thereof, wherein Y represents hydrogen, cyano or carbamoyl; Z represents CH or nitrogen; -A-B- represents -CH2-CH2- or -CH=CH-; m is 1 or 2; and n is 0 or 1. Because of having an extremely potent and selective antagonism to muscarine M3 receptor, these compounds are useful as preventives or remedies for diseases in which muscarine M3 receptor participates. In addition, these compounds can provide safe drugs scarcely causing thirst which is a side effect of muscarine M3 receptor antagonists. |
申请公布号 |
AU3324700(A) |
申请公布日期 |
2000.10.09 |
申请号 |
AU20000033247 |
申请日期 |
2000.03.22 |
申请人 |
MITSUBISHI-TOKYO PHARMACEUTICALS, INC. |
发明人 |
NOBUYUKI YASUDA;JUN-ICHI ENDOH;MASATAKA MIURA;HIDEYUKI AIZAWA;NORIO OHNO |
分类号 |
C07D233/06;A61K31/00;A61K31/415;A61K31/4164;A61P1/00;A61P1/08;A61P11/00;A61P11/06;A61P13/00;A61P25/00;A61P43/00;C07D233/58;C07D521/00 |
主分类号 |
C07D233/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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