CARBOCYCLIC SULFONAMIDE DERIVATIVES

摘要

Sulfonamide derivatives having matrix metalloprotease inhibiting effects, which are compounds represented by general formula (I), optical isomers of the same, pharmaceutically acceptable salts of both, or hydrates thereof wherein R<1> is hydrogen, optionally substituted lower alkyl, or the like; R<2> is a single bond, optionally substituted arylene, or the like; R<3> is a single bond, -CC-, or the like; R<4> is optionally substituted aryl or the like; M is hydroxyl or the like; and m is 0 or 1.