发明名称 GLUCOKINASE ACTIVATORS
摘要 The present invention relates to compounds of formula (I) wherein R<1>, R<2>, R<3> and R<4> are as defined in claim 1 and pharmaceutically acceptable salts thereof. The compounds are glucokinase activators which increase insulin secretion in the treatment of type II diabetes.
申请公布号 WO0058293(A2) 申请公布日期 2000.10.05
申请号 WO2000EP02450 申请日期 2000.03.20
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BIZZARRO, FRED, THOMAS;CORBETT, WENDY, LEA;FOCELLA, ANTONINO;GRIPPO, JOSEPH, FRANCIS;HAYNES, NANCY-ELLEN;HOLLAND, GEORGE, WILLIAM;KESTER, ROBERT, FRANCIS;MAHANEY, PAIGE, E.;SARABU, RAMAKANTH
分类号 A61K31/17;A61K31/4168;A61K31/42;A61K31/421;A61K31/426;A61K31/433;A61K31/4402;A61K31/455;A61K31/50;A61K31/505;A61P3/10;A61P43/00;C07C275/50;C07C317/44;C07C323/60;C07C323/62;C07D;C07D213/75;C07D213/80;C07D213/803;C07D213/82;C07D233/88;C07D237/20;C07D237/22;C07D239/42;C07D241/28;C07D253/07;C07D261/14;C07D263/34;C07D263/48;C07D277/20;C07D277/38;C07D277/46;C07D277/56;C07D277/58;C07D285/12;C07D285/135;(IPC1-7):C07D277/46;C07D213/85;C07D241/20;C07D253/06;A61K31/416;A61K31/440;A61K31/496;A61K31/501;A61K31/53 主分类号 A61K31/17
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