发明名称 |
USE OF BENZOYLGUANIDINES FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS |
摘要 |
(57) Abstract The invention relates to the use of benzoylguanidines of formula (I) wherein R<1> is A; R<2> is Het, CnFmH2n+1-mOp, R<4>, OR<4>, OH, benzyl, CN, Hal, SOq-R<5>, Ph, O-Ph, O-Het, NH-Het, NH2, NHA, NA2 or NH-Ph; R<3> is SO2A'; R<4> is a straight-chain or branched alkyl radical having 1 to 8 C atoms or cycloalkyl having 3 to 8 C atoms which can be unsubstituted or mono-, di- or trisubstituted by A; R<5> is A or Ph; A, A' in each case independently of one another are alkyl having 1 to 6 C atoms, and/or their physiologically acceptable salts and solvates for the production of a medicament for the treatment of non-insulin-dependent diabetes mellitus.
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申请公布号 |
WO0030624(A3) |
申请公布日期 |
2000.10.05 |
申请号 |
WO1999EP08795 |
申请日期 |
1999.11.16 |
申请人 |
MERCK PATENT GMBH;GERICKE, ROLF;BAUMGARTH, MANFRED;MINCK, KLAUS;MESANGEAU, DIDIER;DOARE, LILIANE;KERGOAT, MICHELINE |
发明人 |
GERICKE, ROLF;BAUMGARTH, MANFRED;MINCK, KLAUS;MESANGEAU, DIDIER;DOARE, LILIANE;KERGOAT, MICHELINE |
分类号 |
C07D207/327;A61K31/155;A61K31/166;A61K31/40;A61K31/402;A61P3/10;A61P5/48;C07C279/22;(IPC1-7):A61K31/155 |
主分类号 |
C07D207/327 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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