The present invention relates to compounds of formula (I) wherein R1, R2, R3 and R4 are as defined in claim 1 and pharmaceutically acceptable salts thereof. The compounds are glucokinase activators which increase insulin secretion in the treatment of type II diabetes.
申请公布号
CA2368347(A1)
申请公布日期
2000.10.05
申请号
CA20002368347
申请日期
2000.03.20
申请人
F. HOFFMANN-LA ROCHE AG
发明人
FOCELLA, ANTONINO;MAHANEY, PAIGE E.;KESTER, ROBERT FRANCIS;CORBETT, WENDY LEA;BIZZARRO, FRED THOMAS;HAYNES, NANCY-ELLEN;SARABU, RAMAKANTH;HOLLAND, GEORGE WILLIAM;GRIPPO, JOSEPH FRANCIS
