| 发明名称 |
MODULATION OF VASCULAR PERMEABILITY BY MEANS OF TIE2 RECEPTOR ACTIVATORS |
| 摘要 |
The present invention provides for a method of decreasing or inhibiting vascular permeability and/or plasma leakage in a mammal comprising administering to the mammal a TIE2 receptor activator. The invention also provides for a method of decreasing or inhibiting vascular permeability and/ or plasma leakage in a mammal comprising administering to the mammal an Ang-2 inactivator such as an anti-Ang-2 neutralizing antibody.
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| 申请公布号 |
CA2368670(A1) |
申请公布日期 |
2000.10.05 |
| 申请号 |
CA20002368670 |
申请日期 |
2000.03.20 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;REGENERON PHARMACEUTICALS, INC. |
发明人 |
SURI, CHITRA;YANCOPOULOS, GEORGE D.;THURSTON, O. GAVIN;MCDONALD, DONALD |
| 分类号 |
A61K38/00;A61K38/18;A61K39/395;A61P7/00;A61P9/00;A61P11/00;A61P11/06;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P27/02;A61P29/00;A61P31/04;A61P35/00;C07K16/22;(IPC1-7):A61K38/17 |
主分类号 |
A61K38/00 |
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