发明名称 Z-STYRYL SULFONE ANTICANCER AGENTS
摘要 <p>(Z)-styryl benzylsulfones of formula (I) are useful as anticancer agents: wherein R1 is selected from the group consisting of hydrogen, chloro and nitro; R2 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, chloro, bromo, iodo and fluoro; and R3 and R4 are independently selected from the group consisting of hydrogen, lower akyl, nitro, chloro, bromo, iodo and fluoro; provided that at least one of R1 or R2 is hydrogen. The corresponding (Z)-styryl benzylsulfides are useful as intermediates in the preparation of the biologically active (Z)-styryl benzyl sulfones.</p>
申请公布号 WO2000057872(A1) 申请公布日期 2000.10.05
申请号 US2000008350 申请日期 2000.03.30
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