| 摘要 |
An implantable lead, comprising an electrode which includes a mechanical fastener (e.g. fixation helix). The implantable electrode having at least one of the features: a) the helix having a coating of an insulating material on its surface, b) the helix having its surface beyond the distal end of the electrode and the distal end of the electrode having a porous conductive surface at a base of the helix, c) a porous conductive element, screen or mesh at a base of the helix, and d) a porous conductive element at the end of the electrode having an insulating coating covering from 5-95 % of the surface of the porous conductive element. The electrode may further include an electrode tip having a porous electrical conductive element, such as a mesh screen, disposed on a surface at the distal end of the electrode tip, which can be used as a sensing or pacing interface with the cardiac tissue. In combination with the high impedance tip, a drug delivery system is provided; at least the majority of which drug delivery system is provided from a source within a volume which is within the structural walls of the lead and/or the tip area.
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