Ruthenium-optically active phosphine complex mixture, process for the preparation thereof and asymmetric hydrogenation catalyst comprising same

摘要

The present invention provides a ruthenium-optically active phosphine complex mixture comprising three complexes represented by the following general formulae (I), (II) and (III), respectively: ÄRu(R<1>-SEGPHOS) (sol)4ÜI2 ÄRu(R<1>-SEGPHOS) (sol)4ÜI(anion) ÄRuI(R<1>-SEGPHOS) (sol)3Ü (anion) wherein sol represents a nitrile-based solvent; R<1>-SEGPHOS represents an optically active tertiary phosphine represented by the following general formula (IV): <CHEM> wherein R<1> represents an aryl group which may have a substituent selected from the group consisting of a C1-4 lower alkyl group, a C1-4 lower alkoxy group, a C1-4 lower alkylamino group and a halogen atom, or a C3-9 cycloalkyl group; and anion represents a perfluoroalkylsulfonyl anion, a process for the preparation thereof and an asymmetric hydrogenation catalyst comprising the ruthenium-optically active phosphine complex mixture.