| 发明名称 |
Lxr modulators |
| 摘要 |
The invention provides compounds, compositions and methods for modulating the effects of LXR in a cell. The compounds and compositions are useful both as diagnostic indicators of LXR function and as pharmacologically active agents. The compounds and compositions find particular use in the treatment of disease states associated with cholesterol metabolism, particularly atherosclerosis and hypercholesterolemia. |
| 申请公布号 |
AU3627300(A) |
申请公布日期 |
2000.10.04 |
| 申请号 |
AU20000036273 |
申请日期 |
2000.03.15 |
| 申请人 |
TULARIK, INC. |
发明人 |
LEPING LI;JULIO C. MEDINA;HIROHIKO HASEGAWA;SERENA T. CUTLER;JIWEN LIU;LIUSHENG ZHU;BEI SHAN;KEVIN LUSTIG |
| 分类号 |
C07D295/10;A61K31/136;A61K31/167;A61K31/17;A61K31/18;A61K31/192;A61K31/196;A61K31/235;A61K31/24;A61K31/27;A61K31/277;A61K31/351;A61K31/381;A61K31/40;A61K31/404;A61K31/4164;A61K31/4188;A61K31/42;A61K31/4245;A61K31/426;A61K31/429;A61K31/433;A61K31/4406;A61K31/4436;A61K31/47;A61K31/472;A61K31/5375;A61K31/538;A61K31/5415;A61K31/55;A61P3/02;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P19/10;A61P25/30;C07C233/60;C07C233/75;C07C235/42;C07C271/28;C07C271/58;C07C275/32;C07C307/10;C07C311/08;C07C311/21;C07C311/29;C07C311/44;C07C317/14;C07D209/04;C07D209/08;C07D213/71;C07D215/36;C07D215/58;C07D223/16;C07D261/10;C07D265/36;C07D271/08;C07D271/12;C07D277/20;C07D277/54;C07D279/02;C07D285/14;C07D295/185;C07D295/20;C07D295/215;C07D309/14;C07D333/34;C07D333/40;C07D333/42;C07D409/04;C07D409/12;C07D413/12;C07D513/04 |
主分类号 |
C07D295/10 |
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