发明名称 |
Screening methods for compounds useful in the regulation of cell proliferation |
摘要 |
The present invention relates to drug screening assays and methods for the treatment of proliferative disorders associated with elevated levels of heat shock protein 72 (Hsp72) expression in a cell. The invention is based on the discovery that overexpression of full length Hsp72 protein, or the C-terminal protein binding domain of Hsp72, results in oncogenic transformation of cells. |
申请公布号 |
AU3763900(A) |
申请公布日期 |
2000.10.04 |
申请号 |
AU20000037639 |
申请日期 |
2000.03.17 |
申请人 |
PHYLOGENY, INC. |
发明人 |
VLADIMIR Z. VOLLOCH;MICHAEL SHERMAN |
分类号 |
A61K38/00;C07K14/47;C07K16/30;C12Q1/42;G01N33/50;G01N33/574 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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