发明名称 |
Process for preparing fluorinated benzyl alcohols and fluorinated benzaldehydes |
摘要 |
Fluorinated benzaldehydes are obtainable in a simple and inexpensive manner and in significantly improved yields when chlorinated benzaldehydes are reacted with alkali metal fluorides at temperatures in the range from about 130 to 200 DEG C. in the presence of less than about 2 mol % of quaternary phosphonium salts, based on chlorine atoms to be replaced, at initial concentrations of more than 2.5 mol of the chlorinated benzaldehydes per kg of dipolar aprotic solvent. Fluorinated benzaldehydes obtained in this way can advantageously be hydrogenated with hydrogen in the presence of noble metal catalysts to give fluorinated benzyl alcohols.
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申请公布号 |
US6127581(A) |
申请公布日期 |
2000.10.03 |
申请号 |
US19990369987 |
申请日期 |
1999.08.06 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
WIEDEMANN, JUERGEN;MARHOLD, ALBRECHT;DREISBACH, CLAUS |
分类号 |
B01J23/44;B01J31/02;C07B61/00;C07C29/141;C07C29/153;C07C33/46;C07C45/63;C07C47/55;(IPC1-7):C07C45/63 |
主分类号 |
B01J23/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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