发明名称 Compounds with growth hormone releasing properties
摘要 Novel peptide derivatives, compositions containing them, and their use for treating medical disorders resulting from a deficiency in growth hormone are disclosed. The peptides have the formula (I): wherein a, b, A, R1, L1, D, R3, R4, R2, L2, E and G are as defined in the specification. These peptides exhibit improved resistance to proteolytic degradation, and hence, improved bioavailability.
申请公布号 US6127354(A) 申请公布日期 2000.10.03
申请号 US19990270862 申请日期 1999.03.17
申请人 NOVO NORDISK A/S 发明人 PESCHKE, BERND;ANKERSEN, MICHAEL;HANSEN, THOMAS KRUSE;THOEGERSEN, HENNING
分类号 A61K31/165;A61K31/17;A61K31/18;A61K31/27;A61K31/381;A61K31/40;A61K31/472;A61K31/495;A61P5/06;C07C237/22;C07C243/34;C07C281/06;C07C311/08;C07C311/21;C07D207/08;C07D211/06;C07D217/06;C07D241/08;C07D333/20;(IPC1-7):A61K31/381;A61K31/166;A61K31/135;C07D333/16 主分类号 A61K31/165
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