| 发明名称 |
INHIBITION OF SMOOTH MUSCLE CELL MIGRATION BY (R)-AMLODIPINE |
| 摘要 |
<p>PCT No. PCT/EP94/02697 Sec. 371 Date Feb. 21, 1996 Sec. 102(e) Date Feb. 21, 1996 PCT Filed Aug. 10, 1994 PCT Pub. No. WO95/05822 PCT Pub. Date Mar. 2, 1995The R(+) isomer of amlodipine is a potent inhibitor of smooth muscle cell migration despite its lack of calcium channel-blocking activity. It is useful for treating atherosclerosis, re-stenosis after angioplasty and endometriosis.</p> |
| 申请公布号 |
GR3033547(T3) |
申请公布日期 |
2000.09.29 |
| 申请号 |
GR20000401239T |
申请日期 |
2000.05.31 |
| 申请人 |
PFIZER LIMITED;PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. |
发明人 |
CHAHWALA, SURESH BABUBHAI;WINSLOW, DEREK PAUL |
| 分类号 |
C07D211/78;A61K31/00;A61K31/44;A61K31/4422;A61P9/00;A61P9/08;A61P9/10;A61P13/02;A61P15/00;A61P15/04;A61P43/00;C07D211/90;(IPC1-7):A61K31/44 |
主分类号 |
C07D211/78 |
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