发明名称 PROCESS OF PREPARING FIBRINOGEN RECEPTOR ANTAGONISTS AND INTERMEDIATE FOR CARRYING OUT THE PROCESS
摘要 The invention relates to a process of preparing the fibrinogen receptor antagonists and to an intermediate for carrying out the process. According to the invention, the process consists in preparing the compounds of the structural formula: wherein R 1 is a saturated or unsaturated 6-atom heterocycle comprising one or two heteroatoms, wherein the heteroatoms are N or NR 6, where R 6 is H or C 1 - 10 alkyl; m is an integer from 2 to 6 and R 4 is aryl, C 1- 10 alkyl or C 4-10 aralkyl.
申请公布号 RO116016(B1) 申请公布日期 2000.09.29
申请号 RO19940001433 申请日期 1993.02.23
申请人 MERCK & CO, INC, RAHWAY 发明人 CHUNG JOHN YL;HUGHES DAVID L;ZHAO DALIAN
分类号 C07D211/22;A61K31/4409;A61K31/4418;A61K31/445;A61K31/4465;A61P43/00;C07C309/07;C07C311/06;C07C311/13;C07D211/24;C07D213/30;C07D213/34;(IPC1-7):C07D211/22;C07D311/06 主分类号 C07D211/22
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