摘要 |
Disclosed are pharmaceutical compositions and formulations comprising benzoquinoline derivatives having formulas (I) to (V). In formula (I), X i selected from the group consisting of O, S, CH2, CH2-CH2, C=O or NR8; Z is C or N; R1, R2, R3, and R4 are independently selected from the group consisting of hydrogen, halogen, linear or branched chain lower alkyl, alkenyl, alkynyl, alkoxy or acyl; X-RA and R3, or R3 and R4 are optionally linked together to form a ring or a salt thereof, and a pharmaceutically acceptable carrier or diluent. Also disclosed are methods of inhibiting bacterial growth, comprising the administration of formulations comprising the compounds of formulas (I) to (V).
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申请人 |
SCRIPTGEN PHARMACEUTICALS, INC.;LAM, KELVIN;BOYD, VINCENT;XIANG, YI, BIN |
发明人 |
LAM, KELVIN;BOYD, VINCENT;XIANG, YI, BIN |