发明名称 |
METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES |
摘要 |
Methods for the preparation of biphenyl isoxazole sulfonamides and intermediates thereof. The present invention also relates to the novel intermediates prepared by these methods. The biphenyl isoxazole sulfonamides prepared by the present methods are endothelin antagonists useful, inter ali a, for the treatment of hypertension, congestive heart failure and male erectil e dysfunction.
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申请公布号 |
CA2367916(A1) |
申请公布日期 |
2000.09.28 |
申请号 |
CA20002367916 |
申请日期 |
2000.03.02 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
THOTTATHIL, JOHN K.;POLNIASZEK, RICHARD P.;WANG, XUEBAO;DELANEY, EDWARD J.;SINGH, AMBARISH;CHEN, CHIEN-KUANG;GROSSO, JOHN A. |
分类号 |
A61K31/421;A61K31/422;A61P9/04;A61P9/12;A61P15/10;C07C303/22;C07C309/32;C07D231/12;C07D233/54;C07D233/56;C07D233/60;C07D233/61;C07D233/66;C07D233/78;C07D233/80;C07D233/84;C07D233/86;C07D233/91;C07D261/16;C07D263/32;C07D263/50;C07D277/22;C07D277/24;C07D277/26;C07D277/28;C07D413/12;C07F5/02;(IPC1-7):C07C15/12;C07C25/02;C07C235/02;C07D207/02;C07D231/02;C07D261/02;C07D263/02;C07D275/02;C07D277/02;C07D307/02;C07D261/06;C07D261/08;C07D231/10;C07D261/10;C07D407/10;C07D409/10;C07D413/10;C07D417/10;C07D407/12;C07D409/12;C07D417/12;C07C15/14;C07D231/14;C07D261/14;C07C311/15;C07D231/16;C07D231/18;C07C311/20;C07D277/20;C07D231/24;C07D263/30;C07D207/32;C07D207/34;C07D307/34;C07C303/36;C07D207/36;C07D307/36;C07C303/38;C07D231/38;C07D307/38;C07C235/42;C07D207/42;C07D231/42;C07D231/44;C07C235/48;C07D231/52;C07C309/63;C07C233/64;C07C309/64;C07C233/65;C07C309/65;C07C233/68;C07C309/72;C07C233/73;C07C309/73 |
主分类号 |
A61K31/421 |
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