| 摘要 |
The invention relates to the use of certain low affinity NMDA antagonists as antidepressant agents. Preferred compounds include compounds of formula (I) wherein R1 is pyridyl, phenyl or 4-fluorophenyl; R2 is phenyl or 4- fluorophenyl; R3 is hydrogen, C1-6 alkyl or methoxycarbonyl; R4 is hydrogen or methyl; and R5 is hydrogen or COCH2NH2, and pharmaceutically acceptable salt s thereof.
|
