METHODS FOR DETECTING, PREVENTING, AND TREATING RENAL DISORDERS BY MODULATING, REGULATING, AND INHIBITING CONNECTIVE TISSUE GROWTH FACTOR

摘要

The present invention relates to methods for detecting, preventing, and treating the progression of pathologies characterized by an accumulation of the extracellular matrix components by providing an agent to regulate, inhibit, or modulate the activity of Connective Tissue Growth Factor (CTGF). The method of the present invention is directed to treating kidney fibrosis and associated renal disorders, in particular, complications associated with diabetes and hypertension.