发明名称 |
Compounds and methods for stimulating gene expression and cellular differentiation |
摘要 |
Modulating agents for inhibiting an interaction between alpha-catenin and beta-catenin are provided. The modulating agents comprise one or more of: (a) a beta-catenin HAV motif; (b) a peptide analogue or mimetic of a beta-catenin HAV motif; or (c) an antibody or antigen-binding fragment thereof that specifically binds to a beta-catenin HAV motif. Methods for using such modulating agents for inhibiting cadherin-mediated cell adhesion in a variety of contexts are also provided. |
申请公布号 |
AU2899800(A) |
申请公布日期 |
2000.09.28 |
申请号 |
AU20000028998 |
申请日期 |
2000.03.07 |
申请人 |
MCGILL UNIVERSITY |
发明人 |
OREST W. BLASCHUK;BARBARA J. GOUR |
分类号 |
A61K38/00;C07K14/47;C07K14/705 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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