发明名称 |
Camptothecin derivatives having antitumor activity |
摘要 |
Derivatives of camptothecin of formula (I) <CHEM> wherein the groups R1, R2 and R3 are as defined in the description are disclosed. The compounds of formula (I) are endowed with antitumor activity and show a good therapeutic index. Processes for the preparation of the compounds of formula (I) and their use in the preparation of medicaments useful in the treatment of tumors are also disclosed. |
申请公布号 |
AU3160400(A) |
申请公布日期 |
2000.09.28 |
申请号 |
AU20000031604 |
申请日期 |
2000.03.08 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE S.P.A.;ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI |
发明人 |
SERGIO PENCO;LUCIO MERLINI;FRANCO ZUNINO;PAOLO CARMINATI |
分类号 |
A61K31/4745;A61P31/12;A61P33/06;A61P35/00;C07D491/22 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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