发明名称 |
MOOD DISORDER GENE |
摘要 |
The present invention comprises the use of an 8.9 cM region of human chromosome 18q disposed between polymorphic markers D18S68 and D18S979 or a fragment thereof for identifying at least one human gene, including mutated and polymorphic variants thereof, which is associated with mood disorders or related disorders. The invention also provides methods for determining the susceptibility of an individual to mood disorders or related disorders, comprising analysing a DNA sample for the presence of a trinucleotide repeat expansion in the above region. Polynucleotide sequences useful for detecting the presence of such trinucleotide repeat expansions are also provided. |
申请公布号 |
EP1038015(A2) |
申请公布日期 |
2000.09.27 |
申请号 |
EP19980966865 |
申请日期 |
1998.12.17 |
申请人 |
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE |
发明人 |
VAN BROECKHOVEN, CHRISTINE;RAEYMAEKERS, PETER;DEL-FAVERO, JURGEN |
分类号 |
A01K67/027;A61K38/00;A61P25/22;A61P25/24;C07K14/47;C12N5/10;C12N15/09;C12Q1/02;C12Q1/68;(IPC1-7):C12N15/85;C07K16/18 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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