CELL-CULTURE AND POLYMER CONSTRUCTS

摘要

Cells grown on a microcarrier are separated from the microcarrier by enzymatically digesting the microcarrier. More specifically, chondrocytes ma y be grown on dextran microcarrier beadlets and then the beadlets digested usi ng dextranase to separate the chondrocytes from the carrier. Cells can also be grown on chitosan microcarriers to be used for implantation. In addition, cells can be grown on polysaccharide polymers to be used as implant devices. Various polymers serve as scaffolds for cells to be used for implantation. T he polymers can be used for cell culture as well as for preparing scaffolds useful for tissue replacement such as cartilage tissue.