| 摘要 |
The subject invention concerns a compound of the formula (i): in which Q represents heteroaryl or heterocyclo optionally substituted with one or more substituents selected from the group consisting of C1-6 alkyl (optionally substituted with one or more halogens), C1-6 alkyl-S(O)n- (where n is 0, 1 or 2), -CO2H (or C1-6 alkyl esters thereof or C1-6 alkyl amides thereof), halogen, C1-6 alkoxy, CN, NO2 and NR7R8; R1-R5, which may be the same or different, each represent C1-6 alkyl (optionally substituted with one or more halogens), C1-6 alkyl-S(O)n- (where n is 0, 1 or 2), -CO2H (or C1-16 alkyl esters thereof or C1-6 alkyl amides thereof), halogen, C1-6 alkoxy, CN, NO2, NR7R8 or H (provided R1-R6 are not all H simultaneously); R6 represents H, C1-6 alkyl, -CO2H (or C1-6 alkyl esters thereof or C1-6 alkyl amides thereof), -CN, C1-6 alkyl optionally substituted by -CO2H (or C1-6 alkyl esters thereof or C1-6 alkyl amides thereof), C1-6 alkoxy or -CN; and R7 and R8, which may be the same or different, each represent H, C1-6 alkyl, C1-6 Alkylcarbonyl, C1-6 alkoxycarbonyl, arylsulphonyl, heteroarylsulphonyl, heterocyclosulphonyl, arylcarbonyl, heteroarylcarbonyl, heterocyclocarbonyl or C1-6 alkylsulphonyl, or R7, R8 and the nitrogen to which they are attached form a 5 or 6 membered heterocyclic ring; and pharmaceutically-acceptable salts thereof.
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