PHARMACEUTICAL PREPARATION FOR TREATING AND/OR PREVENTING FUNCTIONAL DISORDER RELATING TO SYNESTHESIALGIA AGGRAVATED IN COLIC REGION AND/OR DISEASE OF DESCENDING COLON, AND PRODUCTION OF THE PREPARATION

摘要

PROBLEM TO BE SOLVED: To obtain the subject pharmaceutical preparation useful for treating and/or preventing functional disorders relating to synesthesialgia aggravated in colic region of a large-sized mammal and Homo and/or diseases of descending colon by using a specified pyrimidine derivative to produce the preparation. SOLUTION: This pharmaceutical preparation is produced by using 4- chloro-5-[(4,5-dihydro-1H-imidazol-2-yl)-amino]-6-methoxy-methylpyrimi dine and its physiologically acceptable acid addition salt. The preparation is preferably administered at a daily dose of about 0.25-3 mg when orally administered to Homo for generally treating functional disorders and/or diseases of descending colon, especially for treating and/or preventing, for example, visceral pain accompanied with the above disorders and/or diseases.