发明名称 IMPROVED PROCESS FOR ASYMMETRIC HYDROGENATION
摘要 <p>The present invention is a process for the preparation of a compound of formula (VIII) where R3, R4 and n are defined in the specification which comprises hydrogenating a compound of formula (VII) the E-geometrical isomer thereof or a mixture of the Z- and E-isomers in the presence of catalyst containing Rh, a chiral ligand with at least one phosphorous atom where the hydrogenation is conducted in the presence of a base.</p>
申请公布号 WO2000055150(A1) 申请公布日期 2000.09.21
申请号 US2000003720 申请日期 2000.03.14
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