发明名称 AMIDE DERIVATIVES
摘要 This invention concerns amide derivatives of Formula (I) wherein X is CH or N; Y is CH or N; m is 0-3; R<1> is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and carbamoyl; n is 0-3; R<2> is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and (1-6C)alkoxycarbonyl; R<3> is hydrogen, halogeno, (1-6C)alkyl or (1-6C)alkoxy; q is 0-4; and Q is a group such as aryl, aryloxy, aryl-(1-6C)alkoxy, arylamino, <u>N</u>-(1-6C)alkyl-arylamino and aryl-(1-6C)alkylamino; or pharmaceutically-acceptable salts or <u>in-vivo</u>-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.
申请公布号 WO0055120(A1) 申请公布日期 2000.09.21
申请号 WO2000GB00914 申请日期 2000.03.13
申请人 ASTRAZENECA AB;BROWN, DEARG, SUTHERLAND 发明人 BROWN, DEARG, SUTHERLAND
分类号 A61K31/167;A61K31/277;A61K31/444;A61K31/5377;A61K31/551;A61P1/00;A61P1/02;A61P1/04;A61P5/18;A61P7/02;A61P7/08;A61P9/00;A61P9/02;A61P9/10;A61P9/12;A61P11/00;A61P11/02;A61P11/06;A61P17/06;A61P19/02;A61P19/08;A61P19/10;A61P25/28;A61P29/00;A61P43/00;C07C237/42;C07C255/57;C07D213/81;C07D213/82;C07D401/14;(IPC1-7):C07C237/42;A61K31/44;A61K31/496 主分类号 A61K31/167
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