发明名称 GAMMA-KETOACID DIPEPTIDES AS INHIBITORS OF CASPASE-3
摘要 Compounds represented by formula (I):as well as pharmaceutically acceptable salts, esters and hydrates thereof are disclosed along with pharmaceutical compositions and methods of treatment. The compounds are useful as inhibitor s of caspase-3, which is implicated in modulating apoptosis.
申请公布号 CA2367862(A1) 申请公布日期 2000.09.21
申请号 CA20002367862 申请日期 2000.03.13
申请人 MERCK FROSST CANADA & CO. 发明人 PRASIT, PETPIBOON;BLACK, CAMERON;BAYLY, CHRISTOPHER;GIROUX, ANDRE;MCKAY, DANIEL;HAN, YONGXIN;ZAMBONI, ROBERT;FRANCOEUR, SEBASTIEN;GRIMM, ERICH;ASPIOTIS, RENEE
分类号 C12N9/99;A61K38/00;A61P3/10;A61P9/10;A61P17/14;A61P21/00;A61P25/00;A61P25/16;A61P25/28;A61P31/18;A61P37/02;C07C323/59;C07D239/34;C07K5/06;(IPC1-7):C07C323/59;C07D271/06;A61K31/198 主分类号 C12N9/99
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