| 发明名称 |
DERIVATIVES OF CHROMONE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION |
| 摘要 |
organic chemistry, pharmacy. SUBSTANCE: invention relates to the novel derivatives of chromone of the general formula (I) where ring A is unsubstituted or monosubstituted with halogen atom and where ring B is unsubstituted or substituted with one-four substituents taken among the group consisting of lower alkyl, hydroxyl, lower alkoxyl, lower alkylthio-group or halogen atom and their salts. Invention describes also method of their synthesis and pharmaceutical composition based on compounds of the formula (I) that shows antagonistic effect with respect to neurokinin-1. EFFECT: new compounds indicated above, valuable medicinal properties. 12 cl, 7 ex
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| 申请公布号 |
RU2156250(C2) |
申请公布日期 |
2000.09.20 |
| 申请号 |
RU19960107121 |
申请日期 |
1996.04.11 |
| 申请人 |
NOVARTIS AG |
发明人 |
D-R ANDREAS FON SHPREKHER;D-R MARK GERSHPAKHER;D-R ROBERT MAN;D-R SIL'VIO ROGGO;D-R VAL'TER SHILLING;D-R SIL'VIO OFNER;D-R SIM JAKOB VEENSTRA |
| 分类号 |
A61K31/352;A61K31/4402;A61K31/443;A61K31/445;A61K31/4468;A61P1/00;A61P1/08;A61P1/12;A61P3/12;A61P9/00;A61P9/08;A61P9/12;A61P11/00;A61P11/06;A61P11/08;A61P25/00;A61P25/04;A61P25/08;A61P25/20;A61P25/24;A61P25/26;A61P29/00;A61P35/00;A61P37/00;A61P37/08;A61P43/00;C07D405/12;(IPC1-7):C07D405/12;A61K31/440 |
主分类号 |
A61K31/352 |
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