Intermediates and process for the manufacture of camptothecin derivatives (CPT-11) and related compounds

摘要

PCT No. PCT/US96/04163 Sec. 371 Date Oct. 2, 1997 Sec. 102(e) Date Oct. 2, 1997 PCT Filed Apr. 1, 1996 PCT Pub. No. WO96/31513 PCT Pub. Date Oct. 10, 1996This invention relates to intermediates and processes for the synthesis of camtothecin derivatives, such as irinotecan. Related procedures and compounds are disclosed, such as a method of making mappicine.