| 发明名称 |
Prostaglandin conjugates for treating or preventing bone disease |
| 摘要 |
This invention relates to prostaglandin-bisphosphonate conjugates. These conjugates are effective for treating or preventing bone diseases such as osteoporosis. These conjugates simultaneously deliver a prostaglandin agent for increasing bone formation and a bisphosphonate agent for inhibiting bone resorption.
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| 申请公布号 |
US6121253(A) |
申请公布日期 |
2000.09.19 |
| 申请号 |
US19990440351 |
申请日期 |
1999.11.15 |
| 申请人 |
MERCK FROSST CANADA & CO. |
发明人 |
HAN, YONGXIN;YOUNG, ROBERT N.;GIL, LAURENT;RUEL, REJEAN |
| 分类号 |
A61K31/663;A61K47/48;A61P1/02;A61P3/14;A61P5/46;A61P7/00;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P29/00;A61P35/00;C07F9/38;(IPC1-7):A61K31/095;A61K31/12 |
主分类号 |
A61K31/663 |
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