发明名称 |
5-oxoprolinase |
摘要 |
The present invention is directed to isolated nucleic acid molecules encoding mammalian 5-oxoprolinase (m 5-OPase). Expression vectors and host cells comprising the nucleic acid molecules are also provided, as well as methods for increasing or decreasing the expression of m 5-OPase in host cells. The invention further provides a method of screening a substance for the ability of the substance to modify m 5-OPase function, and a method for isolating other m 5-OPase molecules. DNA oligomers and antibodies specific for m 5-OPase are provided, each of which can be used to detect m 5-OPase in a sample.
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申请公布号 |
US6120993(A) |
申请公布日期 |
2000.09.19 |
申请号 |
US19960762428 |
申请日期 |
1996.12.09 |
申请人 |
CORNELL RESEARCH FOUNDATION, INC. |
发明人 |
YE, GUO-JIE;BRESLOW, ESTHER;MEISTER ALTON |
分类号 |
C12N9/86;(IPC1-7):C12Q1/68;C12N15/11;C12N15/85;C07H21/04 |
主分类号 |
C12N9/86 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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