| 摘要 |
Disclosed are enantiomers diastereomers, salts, solvates, hydrates and mixtures thereof, of formula I: The core moiety is non-cyclic or at least one five- to seven-membered ring, n is an integer from about 4 to about 16, R1 and R2 are hydrogen, halogen or C1-12 alkyl or alkenyl, and (CH2)n may be substituted by a hydroxyl, halogen, oxygen, a (C1-4) alkyl group or a dimethylamino group. The compounds and pharmaceutical composition thereof are useful in methods for treating an individual having a disease or treatment-induced toxicity, mediated by second messenger activity.
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