发明名称 |
Isolated human cytomegalovirus polypeptides and uses thereof |
摘要 |
Diagnostically relevant polypeptides and fusion proteins comprising an amino acid sequence which originates from cytomegalovirus and corresponds to a region of the major DNA-binding protein or of the C-terminal region of the tegument protein pp150 fused with at least one further fragment from another antigenic protein of cytomegalovirus are disclosed. The major DNA-binding protein is encoded by the reading frame UL57. The poly-peptides and fusion proteins according to the invention can be used in an advantageous manner in diagnostic tests and methods for the detection of IgM antibodies against cytomegalovirus.
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申请公布号 |
US6120989(A) |
申请公布日期 |
2000.09.19 |
申请号 |
US19950506553 |
申请日期 |
1995.07.25 |
申请人 |
BIOTEST AG |
发明人 |
VORNHAGEN, ROLF;HINDERER, WALTER;SONNEBORN, HANS-H.;PLACHTER, BODO;JAHN, GERHARD |
分类号 |
C07K14/045;C07K16/00;C07K19/00;C12N15/09;C12P21/02;C12Q1/68;C12R1/92;G01N33/569;(IPC1-7):C12Q1/70;C07H21/04;A61K39/245 |
主分类号 |
C07K14/045 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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