发明名称 PREVENTION OF FETAL ALCOHOL SYNDROME AND NEURONAL CELL DEATH WITH ADNF POLYPEPTIDES
摘要 The invention relates to methods for reducing a condition associated with fetal alcohol syndrome in a subject who is exposed to alcohol in utero with an ADNF polypeptide (e.g, ADNF I polypeptides, ADNF III polypeptides, or mixtures of ADNF I and ADNF III polypeptides). In one embodiment, the present invention relates to methods for reducing a condition associated with fetal alcohol syndrome in a subject who is exposed to alcohol in utero with a mixture of ADNF I and ADNF III polypeptides. The present invention further relates to methods for reducing neuronal cell death by contacting neuronal cells with a mixture of ADNF I and ADNF III polypeptides. Still further, the present invention relates to a pharmaceutical composition comprising a mixture of ADNF I and ADNF III polypeptides.
申请公布号 WO0053217(A2) 申请公布日期 2000.09.14
申请号 WO2000US06364 申请日期 2000.03.10
申请人 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES;RAMOT OF TEL AVIV UNIVERSITY;BRENNEMAN, DOUGLAS, E.;SPONG, CATHERINE, Y.;GOZES, ILLANA;BASSAN, MERAV;ZAMOSTIANO, RACHEL 发明人 BRENNEMAN, DOUGLAS, E.;SPONG, CATHERINE, Y.;GOZES, ILLANA;BASSAN, MERAV;ZAMOSTIANO, RACHEL
分类号 A61K38/18;A61P25/28;A61P25/32;(IPC1-7):A61K38/18;A61K31/708 主分类号 A61K38/18
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