| 发明名称 |
TARGET CELL-SPECIFIC, MULTIVALENT PROTEINS (MVP) |
| 摘要 |
The invention relates to a target cell-specific, multivalent protein (MVP) characterized in being comprised of the following components which are covalently bound to one another: a) a binding structure (a)n specific for the vector; b) a linker (b)m and; d) at least two binding structures (c)o for the target cell, whereby, independent of one another, n=1, m=1-10 and o=2-10. The invention also relates to the production and use of said multivalent protein.
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| 申请公布号 |
WO0053790(A1) |
申请公布日期 |
2000.09.14 |
| 申请号 |
WO2000EP01612 |
申请日期 |
2000.02.26 |
| 申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
KONTERMANN, ROLAND;NETTELBECK, DIRK;SEDLACEK, HANS-HARALD;MUELLER, ROLF |
| 分类号 |
A61P37/02;C07K14/52;C07K16/08;C07K16/28;C07K19/00;C12N15/12;(IPC1-7):C12N15/87;C07K14/47;C12N15/62;A61K38/12;A61K39/00;C07K16/00;C07K16/46 |
主分类号 |
A61P37/02 |
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