摘要 |
Compounds of formula (I) wherein: R<1> represents a substituent selected from: a hydrogen or halogen atom; a hydroxy, cyano, nitro, trifluoromethyl, trifluoromethoxy, trifluoromethanesulfonyloxy, pentafluoroethyl, C1-4alkyl, C1-4alkoxy, arylC1-4alkoxy, C1-4alkylthio, C1-4alkoxyC1-4alkyl, C3-6cycloalkylC1-4alkoxy, C1-4alkanoyl, C1-4alkoxycarbonyl, C1-4alkylsulfonyl, C1-4alkylsulfonyloxy, C1-4alkylsulfonylC1-4alkyl, arylsulfonyl, arylsulfonyloxy, arylsulfonylC1-4alkyl, C1-4alkylsulfonamido, C1-4alkylamido, C1-4alkylsulfonamidoC1-4alkyl, C1-4alkylamidoC1-4alkyl, arylsulfonamido, arylcarboxamido, arylsulfonamidoC1-4alkyl, arylcarboxamidoC1-4alkyl, aroyl, aroylC1-4alkyl, or arylC1-4alkanoyl group; a group R<5>OCO(CH2)p, R<5>CON(R<6>)(CH2)p, R<5>R<6>NCO(CH2)p or R<5>R<6>NSO2(CH2)p where each of R<5> and R<6> independently represents a hydrogen atom or a C1-4alkyl group or R<5>R<6> forms part of a C3-6azacycloalkane or C3-6(2-oxo)azacycloalkane ring and p represents zero or an integer from 1 to 4; or a group Ar<3>-Z, wherein Ar<3> represents an optionally substituted phenyl ring or an optionally substituted 5- or 6- membered aromatic heterocyclic ring and Z represents a bond, O, S, or CH2; R<2> represents a hydrogen atom or a C1-4alkyl group; R<3> and R<4> each independently represent a C1-4 alkyl group, q is 1 or 2; A represents a group of the formula (a), (b), (c) or (d).
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申请人 |
SMITHKLINE BEECHAM P.L.C.;JOHNSON, CHRISTOPHER, NORBERT;STEMP, GEOFFREY |
发明人 |
JOHNSON, CHRISTOPHER, NORBERT;STEMP, GEOFFREY |