发明名称 METHODS OF TREATING OSTEOARTHRITIS WITH INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS
摘要 Methods of treating and/or preventing osteoarthritis by modulating the amount of fynovial fluid, IL-1 beta levels, the development of osteophytes, the amount of cartilage degeneration, metalloprotease production and acute joint injury through administering an effective amount of an inducible nitric oxide synthase inhibitor are provided.
申请公布号 WO0013709(A3) 申请公布日期 2000.09.14
申请号 WO1999US20545 申请日期 1999.09.07
申请人 MONSANTO COMPANY;MANNING, PAMELA, T.;PELLETIER, JEAN-PIERRE;PELLETIER, JOHANNE, MARTEL;CONNOR, JANE, R.;CURRIE, MARK, G. 发明人 MANNING, PAMELA, T.;PELLETIER, JEAN-PIERRE;PELLETIER, JOHANNE, MARTEL;CONNOR, JANE, R.;CURRIE, MARK, G.
分类号 A61K45/00;A61K31/00;A61K31/198;A61P19/02;A61P43/00;(IPC1-7):A61K31/198 主分类号 A61K45/00
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