发明名称 TRANSDERMAL THERAPEUTIC SYSTEM WHICH CONTAINS A D2 AGONIST AND WHICH IS PROVIDED FOR TREATING PARKINSONISM, AND A METHOD FOR THE PRODUCTION THEREOF
摘要 <p>A transdermal therapeutic system, comprising a backing layer inert to the components of the matrix, a self-adhesive matrix layer containing (-)-5,6,7,8-tetrahydro-6-[propyl-[2-(2-thienyl)ethyl]amino]-1-naphthalenol in an effective amount and a protective foil or sheet to be removed prior to use, is characterised by a matrix that is based on a non-aqueous, acrylate-based or silicone-based polymer adhesive system having a solubility of >=5% (w/w) for (-)-5,6,7,8-tetrahydro-6-[propyl-[2-(2-thienyl)ethyl]-amino]-1-naphthalenol, and said matrix is substantially free of inorganic silicate particulates.</p>
申请公布号 EP1033978(A1) 申请公布日期 2000.09.13
申请号 EP19990910359 申请日期 1999.03.18
申请人 LTS LOHMANN THERAPIE-SYSTEME AG;DISCOVERY THERAPEUTICS, INC. 发明人 MUELLER, WALTER;PECK, JAMES, V.
分类号 A61K9/70;A61K31/381;A61P25/16;A61P43/00;(IPC1-7):A61K9/70 主分类号 A61K9/70
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