发明名称 |
N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for use |
摘要 |
Disclosed are compounds which inhibit beta -amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits beta -amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
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申请公布号 |
US6117901(A) |
申请公布日期 |
2000.09.12 |
申请号 |
US19970976179 |
申请日期 |
1997.11.21 |
申请人 |
ATHENA NEUROSCIENCES, INC.;ELI LILLY & COMPANY |
发明人 |
WU, JING;THORSETT, EUGENE D.;NISSEN, JEFFREY S.;MABRY, THOMAS E.;LATIMER, LEE H.;JOHN, VARGHESE;FANG, LAWRENCE Y.;AUDIA, JAMES E. |
分类号 |
A61K31/198;A61K31/223;A61K31/277;(IPC1-7):A61K31/16 |
主分类号 |
A61K31/198 |
代理机构 |
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代理人 |
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地址 |
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