THE USE OF 4-AMINOPYRIDINE IN THE PREPARATION OF A MEDICAMENT REDUCING PAIN AND SPASTICITY

摘要

The use of 4-aminopyridine to treat a neurological condition is described. In particular, the present invention relates to the use of 4-aminopyridine to treat spinal cord injured individuals. It has been found that 4-aminopyridine can reduce pain and spasticity in a spinal cord injured individual when given in doses from about 18 to about 30 milligrams intravenously or intratecally. The results are quite significant due to the high incidence of these problems and the intractable nature of central pain in the spinal cord injured individuals. 4-aminopyridine is also useful in increasing sensory ability and motor control.