发明名称 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE
摘要 The present invention comprises piperazine-containing compounds which inhibit prenyl-protein transferases, including farnesyl-protein transferase and geranylgeranyl-protein transferase type I. Such therapeutic compounds are useful in the treatment of cancer.
申请公布号 WO0051611(A1) 申请公布日期 2000.09.08
申请号 WO2000US05216 申请日期 2000.03.01
申请人 MERCK & CO., INC.;HARTMAN, GEORGE, D.;LUMMA, WILLIAM, C., JR.;SISKO, JOHN, T.;SMITH, ANTHONY, M.;TUCKER, THOMAS, J.;STOKKER, GERALD, E. 发明人 HARTMAN, GEORGE, D.;LUMMA, WILLIAM, C., JR.;SISKO, JOHN, T.;SMITH, ANTHONY, M.;TUCKER, THOMAS, J.;STOKKER, GERALD, E.
分类号 C07D233/64;A61K31/496;A61P1/16;A61P9/00;A61P9/10;A61P13/12;A61P27/02;A61P31/10;A61P31/12;A61P35/00;A61P35/02;A61P43/00;C07D233/54;C07D401/12;C07D405/12;(IPC1-7):A61K31/495;A61K31/499;A61K31/551;C07D403/04;C07D403/06 主分类号 C07D233/64
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