POLYNUCLEOTIDE AND POLYPEPTIDE SEQUENCES ENCODING HUMAN ORGANIC ANION TRANSPORTER 6(hOATP6) AND SCREENING METHODS THEREOF

摘要

OATP6 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing OATP6 polypeptides and polynucleotides in therapy, and diagnostic assays for such. Futher disclosed is a method for performing a selection screen, whereby compounds are identified that neither agonize nor antagonize the activity of OATP6.