发明名称 |
DETECTION OF MTOC DISRUPTING SUBSTANCES |
摘要 |
A method is provided for identifying a substance capable of disrupting microtubule organising centre (MTOC) integrity, which method comprises: contacting an Asp polypeptide or homologue thereof, or fragment thereof capable of forming and/or maintaining MTOCs in the absence of the substance, with a candidate substance in the presence of components required for MTOC formation and microtubule nucleation therefrom, and determining whether the substance disrupts MTOC integrity. |
申请公布号 |
WO0052478(A1) |
申请公布日期 |
2000.09.08 |
申请号 |
WO2000GB00785 |
申请日期 |
2000.03.03 |
申请人 |
UNIVERSITY OF DUNDEE;GLOVER, DAVID, MOORE;AVIDES, MARIO DO CARMO |
发明人 |
GLOVER, DAVID, MOORE;AVIDES, MARIO DO CARMO |
分类号 |
C07K14/435;C07K16/18 |
主分类号 |
C07K14/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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