发明名称 |
COMPOSITIONS AND METHODS FOR TREATMENT OF STAPHYLOCOCCAL INFECTION |
摘要 |
Co-administration of a lysostaphin or other anti-staphylococcal agent which cleaves cross-links of peptidoglycans of staphylococci cell walls such as lysostaphin and an antibiotic effective against staphylococci due to antibiotic activity mediated by cell-wall activity is effective against staphylococcal infection, even staphylococci that may be resistant to one or other of lysostaphin or the cell-wall active antibiotic. Co-administration simultaneously suppresses the generation of antibiotic-resistant mutant strains. Effective cell-wall active antibiotics include beta -lactams and glycopeptides. |
申请公布号 |
WO0051588(A1) |
申请公布日期 |
2000.09.08 |
申请号 |
WO2000US05464 |
申请日期 |
2000.03.03 |
申请人 |
AMBI INC. |
发明人 |
CLIMO, MICHAEL;MURPHY, ELLEN;ARCHER, GORDON |
分类号 |
A61K45/06 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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