摘要 |
A capsule system for oral delivery of an active agent having low aqueous solubility generally includes, in combination with the active agent, a vehic le for preventing initial active agent dissolution within the gastrointestinal tract and an emulsifier for promoting self-emulsification of the active agen t and vehicle in the gastrointestinal tract. A capsule shell is provided for encapsulating the active agent, vehicle and emulsifier with the shell being formulated to open upon ingestion into the gastrointestinal tract and releas e the active agent and vehicle.
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