| 摘要 |
<p>The present invention provides a lower-dose of remifentanil in a stable formulation suitable for use by general practitioners. Specifically, the present invention provides an aqueous composition prepared for lyophilization comprising remifentanil (or a pharmaceutically acceptable salt or solvate thereof), sodium chloride and hydrochloric acid. The invention further provides a lyophilized solid form composition comprising remifentanil (or a pharmaceutically acceptable salt or solvate thereof) and sodium chloride. The invention yet also provides a lyophilized solid form composition reconstituted into a solution suitable for IV administration comprising remifentanil (or a pharmaceutically acceptable salt or solvate thereof) and sodium chloride.</p> |
