发明名称 COMPOSITION COMPRISING A TRAMADOL MATERIAL AND A SELECTIVE COX-2 INHIBITOR DRUG
摘要 <p>This invention relates to a pharmaceutical composition comprising a combination of a tramadol material and a selective COX-2 inhibitor drug and use for treating or preventing pain, inflammation and certain neurological disorders and cancers. The compositions have a synergistic effect, use less of each ingredient and have less opioid side effects such as abuse liability, tolerance, constipation and respiratory depression.</p>
申请公布号 WO2000051685(A1) 申请公布日期 2000.09.08
申请号 US2000005119 申请日期 2000.02.29
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