发明名称 ASTHMA/ALLERGY THERAPY THAT TARGETS T-LYMPHOCYTES AND/OR EOSINOPHILS
摘要 A pharmaceutical composition for the treatment and/or prophylaxis of diseases caused by type I hypersensitivity reactions consisting essentially of Glicophosphopeptical, or pure Nigella Sativa seeds, in a concentration which stimulate Th1 lymphocytes and selectively switch-off the eosinophilic airway inflammation. A method of treatment of allergy using Th1 stimulating agents, to be administered to a mammal such as human in need of such treatment in a shot of 5 days only, resulted in significant decrease in symptom score started day 3, and in sputum eosinophils by day 14, followed by long-term clinical remission of a mean of 6 months. The BCG-like Th1 stimulation is also used in treating diseases in which the body defensive mechanism is a Cell Mediated Immunity, including viral infections, as but not limited to influenza and common cold, chronic and recurrent urinary tract infection, pelvic inflammatory diseases as neuroimmune appendicitis, cancer, Crohns disease and facial palsy.
申请公布号 WO0051580(A2) 申请公布日期 2000.09.08
申请号 WO2000IB00222 申请日期 2000.03.02
申请人 AL-JASSIM, RAWAA;AL-KAISI, BAN;JAMES, DAVID;NASSIEF, NIDA, ABDUL-GHANI 发明人 NASSIEF, NIDA, ABDUL-GHANI
分类号 A61K36/71;A61P37/04;(IPC1-7):A61K31/00 主分类号 A61K36/71
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